In 1364 the Studium became an imperial university. When the Medici came to power in Tuscany in 1472 it was exiled to Pisa. From that time onward there were frequent transfers between Florence and Pisa according to the different changes in the government. Charles VIII brought back the Studium to Florence between 1497 and 1515. Then, a comeback of the Medici moved it again to Pisa. Throughout this period many teachings and research remained active in Florence supported by the numerous academies that came to flourish in the meantime, such as Accademia della Crusca and Accademia del Cimento.