The origins of the University of Nariño date back to 1712, when the College of the Society of Jesus was established through numerous campaigns and donations from the community, which brought together the sum of 43,000 plantains for the construction of the college the same place where today the headquarters of the University in the center of the city.In mentioned school is located was notable latinidad teaching, Spanish language and church history.
In 1767, following the expulsion of the Jesuits of the territory of America decreed by Carlos III, the school was closed, which affected education regional.En 1791, academic activities were resumed, this time with the name of Real School Seminar which managed to survive many difficulties until 1822, when the city was embroiled in numerous conflicts by its position in defense of Spain.Campus facilities were turned into military barracks and many students swelled the ranks of the armies realistas.Ante Bolivar requests made to restore the college, he ordered the return of the facilities. In 1827, General Francisco de Paula Santander issued a decree which was established in the city of Pasto a provincial school, with chairs of Latin grammar, philosophy, Spanish grammar and more higher education.