The Research Institute for Electronic Science (RIES) of Hokkaido University has more than 20 years of history during which we have worked actively under the mission of development of new interdisciplinary fields. If the Research Institute of Ultrashort Waves, its predecessor, is considered, then more than 70 years have passed since establishment of the organization. Since 2007, we have been participating in a nanotechnology network project for creating outcomes by sharing cutting-edge research equipments and facilities launched by the Ministry of Education, Culture, Sports, Science and Technology (MEXT). We are acting as the hub of "Hokkaido innovation creation nano-engineering and measurement support network" in this program and established nano-technology research center attached to the institute. In 2012, five years after its establishment, the organization was reformed comprehensively to have four departments attached to the institute, including "Photonics and Optical Science", "Material and Molecular Sciences", "Biology and Life Sciences" and "Mathematical and System Sciences" and "Green Nanotechnology Research Center", making a total of five pillars. We are making every effort to accomplish our missions.