Collegium Medicum was previously known as the Ludwik Rydygier Medical University, which was established by the Seym (the lower chamber of the Polish parliament) on 21st July 1984. In October of the same year, the Rector, Prof. dr hab. Jan Domaniewski, inaugurated the youngest medical university in Poland. In 2004, the Medical University in Bydgoszcz was incorporated into the Nicolaus Copernicus University in Toruń and renamed as the Ludwik Rydygier Collegium Medicum in Bydgoszcz. Since then, it has been providing academic education as part of NCU.
In 1971 the Clinical Teaching Team was appointed in Bydgoszcz. Doc. dr hab. Bogdan Romański was chosen the head of the team.In 1973/1974 full-time studies, with all the courses, were organized for thirty eight 5th year students at the Faculty of Medicine.On 1 September 1975 by the decision of The Minister of Health and Social Welfare the Branch of the Medical University of Gdańsk with the seat in Bydgoszcz was established.In May, 1980, a new hospital presently named after Dr Jan Biziel was opened.On 21 July 1984 the Seym [the lower chamber of the Polish parliament] unanimously passed the bill on establishing Medical University in Bydgoszcz. On 1 October 1984 in the concert hall of the Pomeranian Philharmonic Orchestra, the Rector, Prof. dr hab. Jan Domaniewski inaugurated the first year of functioning of the youngest medical university in Poland.