Founded and formally inaugurated during the 19th anniversary celebration of Manila Doctors Hospital (MDH) in 1975 and first known as the Manila Doctors Hospital School of Nursing, the College was originally located at the fourth floor of the Manila Doctors Hospital along United Nations Avenue in Manila. Its founding members include Dr. Ambrosio Tangco, Dr. Gonzalo F. Austria, Dr. Fidel Estrada, Dr. Jose Villanueva and then members of the Board of Directors of MDH. Mrs. Cristeta T. Patajo was the first principal.
